Observational studyGeneral thoracic and cardiovascular surgery2026
A simplified frailty assessment using three objective measures predicts mid-term outcomes after cardiac surgery.
Observational study in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Comments on: A simplified frailty assessment using three objective measures predicts mid-term outcomes after cardiac surgery.General thoracic and cardiovascular surgery · 2026Article
- Response to "Comments on: A simplified frailty assessment using three objective measures predicts mid-term outcomes after cardiac surgery".General thoracic and cardiovascular surgery · 2026Article
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveFrailty is a major risk factor for adverse outcomes following cardiac surgery, yet its routine clinical integration is hindered by the lack of a standardized, convenient assessment method. This study aimed to develop and validate a simplified frailty model using three objective measures: gait speed, serum albumin, and grip strength.
methodsIn this prospective observational study of 261 patients (≥ 65 years) undergoing elective cardiac surgery, frailty was assessed using both the Japanese Cardiovascular Health Study criteria and our simplified model. The model defined frailty as having ≥ 2 of the following: slowness (gait speed < 1.0 m/s), hypoalbuminemia (albumin ≤ 3.5 g/dL), and weakness (grip strength < 28 kg for men, < 18 kg for women).
resultsThe simplified model demonstrated high diagnostic accuracy for frailty defined by the Japanese Cardiovascular Health Study criteria (area under the curve = 0.868; sensitivity, 55.8%; specificity, 91.4%). Frailty defined by our model was a strong predictor of worse 3-year survival (hazard ratio, 10.43; 95% confidence interval, 2.82-38.58; p < 0.001) and event-free survival (hazard ratio, 2.52; 95% confidence interval, 1.47-4.34; p < 0.001), with prognostic power comparable to the Japanese Cardiovascular Health Study criteria.
conclusionsA simplified frailty model incorporating gait speed, serum albumin, and grip strength provides robust diagnostic and prognostic utility. Its objectivity and ease of use may facilitate consistent preoperative risk stratification in patients undergoing cardiac surgery.
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