ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Acupuncture reduced incidence of insomnia symptoms in patients with lung cancer: a retrospective cohort study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeAbout 30-50% of lung cancer patients suffer from insomnia with limited prevention options. We conducted a retrospective cohort study to investigate whether acupuncture for cancer-related symptoms such as pain could reduce the incidence of insomnia symptoms.
methodsWe included newly diagnosed lung cancer patients without prior insomnia symptoms from Guangdong Provincial Hospital of Chinese Medicine (2012-2021) and followed up until January 31, 2022. Cases were propensity score-matched by sex, age, ECOG PS score, pathological diagnosis, therapy, and comorbidities. The main outcome was the incidence of insomnia symptoms, identified by psychiatric diagnosis or insomnia symptoms in medical records.
resultsAmong 1295 lung cancer survivors, 918 patients were matched (459 per group). Over an average follow-up of 218.6 days, insomnia symptoms were observed in 20.9% of the acupuncture group and 42.2% of the non-acupuncture group. Acupuncture was linked to a lower incidence of insomnia symptoms (adjusted HR 0.31, 95% CI 0.23-0.39). Higher frequency and more numerous acupuncture sessions further reduced the risk of insomnia symptoms (adjusted HR 0.15 for frequency of 1 day/session, adjusted HR 0.15 for sessions > 16). The acupuncture group had a significantly lower cumulative incidence of insomnia (log-rank test, P < 0.01).
conclusionOur results suggest that acupuncture may prevent the incidence of insomnia symptoms in patients with lung cancer. Daily sessions and a cumulative total of 16 or more treatments may enhance the benefit.
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