ArticleAbdominal radiology (New York)2026
The role of liver stiffness measurement in predicting Long-term liver function after partial hepatectomy.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo observe liver function changes from pre-operative to post-operative 12 months in patients with treatment-naive hepatocellular carcinoma (HCC) and chronic hepatitis B (CHB) undergoing partial hepatectomy, and explore the utility of peri-operative metrics, including two-dimensional shear wave elastography (2D-SWE) measurements, in predicting the liver function recovery thereof.
methodsTotally 253 patients were prospectively enrolled and followed for one year. Data were collected pre-operatively and at post-operative 5th day and 1st, 3rd, 6th, and 12th months. Variance analysis with Tukey's correction explored the changes in albumin-bilirubin (ALBI)-measured liver function. Logistic regression analyzed the relationship between peri-operative indicators and post-operative liver function recovery (ALBI grade 1). The receiver operating characteristic curve assessed the logistic computation's discrimination.
resultsALBI score increased on post-operative 5th day compared to pre-operative levels (p < 0.001), then fell below pre-operative levels by the post-operative 1st month (p < 0.001) and stabilized by the 3rd month (all p > 0.050). Liver function recovered in 155 (61.3%) patients. The fewer lesions (p = 0.027), lower 2D-SWE measurement value (p = 0.010), lower pre-operative ALBI score (p < 0.001), and the absence of post-hepatectomy liver failure (PHLF; p = 0.030) were the predicting factors of liver function recovery. The derived computation could differentiate the likelihood of liver function recovery at post-operative 1st, 3rd, and 12th months (all p < 0.050).
conclusionsLiver function may stabilize by the post-hepatectomy 3rd month. Pre-operative 2D-SWE measurements, ALBI score, the number of lesions, and PHLF could affect liver function recovery in patients with HCC and CHB.
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