Evidence map›Paper›PMID 41417073›Full record

ArticleAbdominal radiology (New York)2026

CT colonography for longitudinal in-vivo assessment of colonic lengthening in middle-age and older adults.

Perry J Pickhardt, Varun Razdan

Abstract read
In one paragraph

Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Perry J PickhardtDepartment of Radiology, University of Wisconsin School of Medicine & Public Health, Madison, USA. ppickhardt2@uwhealth.org.
Varun RazdanDepartment of Radiology, University of Wisconsin School of Medicine & Public Health, Madison, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough a general trend for longer colons among older adults has been observed, longitudinal demonstration of intra-patient elongation is lacking. We assessed colonic length at serial CT colonography (CTC), which allows for precise length measurement over time.

methodsLongitudinal CTC evaluation (mean time interval, 12.8 years; range, 11.6-16.6 years) in 100 asymptomatic adults (mean age, 54.2 years at index study; 50 men, 50 women) were analyzed using a dedicated software system (V3D Colon, Viatronix). Segmental and total colonic lengths were obtained at interactive 2D and 3D review utilizing the automated luminal centerline.

resultsMean total colonic length increased from 198.1 cm at index CTC to 205.7 cm at follow-up (p < 0.001), corresponding to an annual increase of 0.6 ± 1.2 cm/year. The corresponding median colonic length increased from 191.5 cm to 202.0 cm. Intraperitoneal segments suspended by a mesentery accounted for 80% (6.1 cm) of the average overall 7.6 cm elongation, including a mean increase of 2.1 cm in the sigmoid colon and 4.0 cm in the transverse colon. There was no significant net length change for the extraperitoneal segments (rectum and retroperitoneal colon). Women had a longer colon at initial CTC on average (202.1 cm vs. 194.0 cm) but mean length was similar at final CTC (205.4 cm vs. 206.1 cm) given the increased rate of interval elongation in men (0.88 cm/year in men vs. 0.31 cm/year in women).

conclusionLongitudinal CTC showed a mean age-related increase in colonic length of greater than 7 cm per decade in middle-age and older adults. The intraperitoneal colonic segments (transverse > sigmoid) accounted for most of this elongation, whereas the more fixed extraperitoneal segments showed no significant net length increase.

Indexed as

ColonColonography, Computed TomographicAdultAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleMiddle AgedRadiographic Image Interpretation, Computer-AssistedAnatomyColonCT colonographyLarge intestineVirtual colonoscopy

Identifiers

PMID41417073
PMCPMC13269295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.