Evidence map›Paper›PMID 41417040›Full record

ReviewClinical neuroradiology2026

Patient Management After Flow Diversion for Unruptured Intracranial Aneurysms: a Literature Review and DELPHI Consensus.

Alexander Stebner, Marie-Sophie Schüngel, Salome Lou Bosshart, Satoru Fujiwara, Genevieve Milot, David Volders, Kazutaka Uchida, Christine Hawkes, Petra Cimflova, Manu Moreu and 20 more

Abstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Alexander StebnerDepartment of Neuroradiology, University Hospital of Basel, Basel, Switzerland.
Marie-Sophie SchüngelDepartment of Neuroradiology, University Hospital in Halle, Halle, Germany.
Salome Lou BosshartDepartment of Clinical Neurosciences, University of Calgary, Calgary, Canada.
Satoru FujiwaraDepartment of Neurology, Kobe City Nishi-Kobe Medical Center, Kobe, Japan.
Genevieve MilotDepartment of Surgery, Université Laval, Québec, Canada.
David VoldersDepartment of Radiology, University of Toronto, Toronto, Canada.
Kazutaka UchidaDepartment of Neurosurgery, Hyogo Medical University, Nishinomiya, Japan.
Christine HawkesDivision of Neurology, Sunnybrook Health Science Centre, Toronto, Canada.
Petra CimflovaDepartment of Diagnostic and Interventional Neuroradiology, University Hospital of Bern, Bern, Switzerland.
Manu MoreuRadiology department, Hospital Clínico San Carlos, Madrid, Spain.
Isabel FragataDepartment of Neuroradiology, ULS São José, Lisbon, Portugal.
Alexandra PaulDepartment of Neurosurgery, Albany Medical Center Hospital, Albany, United States.
Umberto PensatoDepartment of Neurology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Christian UlfertDepartment of Neuroradiologie, University Hospital Heidelberg, Heidelberg, Germany.
Donald FreiColorado Neurological Institute, Denver, United States.
Pervinder BhogalDepartment of Neuroradiology, Royal London Hospital, London, United Kingdom.
Joanna SchaafsmaDepartment of Medical Imaging, University Health Network, Toronto, Canada.
Sandor NardaiCenter of Neurosurgery and Neurointervention, Semmelweis University, Budapest, Hungary.
Syed ZaidiDepartment of Neurology,, University of Toledo, Toledo, United States.
Mohammed AlmekhlafiDepartment of Clinical Neurosciences, University of Calgary, Calgary, Canada.
Shahid NimjeeThe Ohio State University Wexner Medical Center, Columbus, United States.
Pascal MosimannDepartment of Radiology, University of Toronto, Toronto, Canada.
James KennedyJohn Radcliffe Hospital, Oxford, United Kingdom.
Jeremy RempelDepartment of Radiology, University of Alberta, Edmonton, Canada.
Violoza InoaDepartment of Neurology, University of Tennessee Health Science Center, Memphis, United States.
Shinichi YoshimuraDepartment of Neurosurgery, Hyogo Medical University, Nishinomiya, Japan.
Marc RiboDepartment of Neurology, Vall d'Hebron Hospital Universitari, Barcelona, Spain.
Demetrius LopesCerebrovascular and Comprehensive Stroke Center, Advocate Illinois Masonic Medical Center, Chicago, United States.
John WongDepartment of Clinical Neurosciences, University of Calgary, Calgary, Canada.
Johanna OspelDepartment of Clinical Neurosciences, University of Calgary, Calgary, Canada. johanna.ospel@ucalgary.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnruptured intracranial aneurysms are a common and can have devastating outcomes if ruptured. Flow diversion has expanded treatment options, especially for wide-necked and blister aneurysms. Yet, optimal follow-up retreatment strategies in case of treatment failure remain unclear. A DELPHI consensus was initiated to understand current practice in aneurysm management after flow diverter treatment.

methodsThis DELPHI consensus was conducted during the 5 T Think Tank, following a scoping literature review. Experts discussed the results, responded to iterative questionnaires, which started with four open-ended questions, and concluded with ten closed-ended questions.

resultsOf the 40 attendees, 24 participants (60%) identified as experts in flow diversion and participated in the DELPHI process, which involved a literature search and three DELPHI rounds. Consensus was reached on performing the first assessment of the flow diverter during the procedure using cone-beam CT (77.8%), and on timing of the first follow up (at 6 months, 70.8%). For follow-up timing, an annual (57%) or semi-annual (43%) schedule was favored. No preference emerged for the follow-up imaging modality, with slight preferences for MRA (29%), followed by DSA (25%), DSA + MRA (21%), CTA (17%), and DSA + CTA (8%). Aneurysm growth (> 2 mm) was identified as a key criterion for retreatment. It was thought that combining clinical and angiographic metrics should be a key research priority, as it could potentially improve retreatment decision making compared to a purely angiographic outcome.

conclusionThis DELPHI consensus highlights the complexity of decision-making for unruptured intracranial aneurysms. Despite these challenges, there was consensus among international experts on follow-up timing and decision drivers for retreatment.

Indexed as

Endovascular ProceduresIntracranial AneurysmCerebral AngiographyDelphi TechniqueHumansStentsAneurysmFlow diverterHemorrhagic strokeNeuroimagingSubarachnoid hemorrhage

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.