Evidence map›Paper›PMID 41416617›Full record

ArticlePediatric pulmonology2025

A Comparative Bibliometric Analysis of Pediatric Interstitial Lung Disease Treatment: Global Trends, Advances, and Future Directions (2004-2024).

Lina Ma, Ling Yang, Sujing Su, Wenxia Chen

Abstract readComparative Study
In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lina MaPICU/The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.ORCID https://orcid.org/0009-0005-8031-8346
Ling YangPICU/The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Sujing SuPICU/The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Wenxia ChenPICU/The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.ORCID https://orcid.org/0009-0005-9320-0099

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundChildhood interstitial lung disease (chILD) is rare, heterogeneous, and presents major treatment challenges. This bibliometric study analyzes research trends and hotspots specifically within the domain of chILD treatment research.

methodsUsing bibliometrics, this study utilized data from the Web of Science Core Collection spanning from 2004 to 2024. Various research hotspots were analyzed using VOSviewer, CiteSpace, and the R package "bibliometric."

resultsA total of 577 articles were examined. Prominent journals contributing to this field included Pediatric Pulmonology, Thorax, and the European Respiratory Journal. Griese Matthias, Schwerk Nicolaus, and Clement Annick emerged as the most productive and cited authors. The study identified five key research directions: (1) genetic and molecular mechanisms, (2) clinical management, (3) neonatal risk factors, (4) autoimmune-related factors and immunomodulatory therapies, and (5) fibrosis progression. Keyword analysis showed a recent surge (2022-2024) in research on autoimmune and inflammatory factors, with notable bursts in "polymyositis" and "juvenile dermatomyositis," alongside growing attention to immunosuppressive therapies such as "mycophenolate-mofetil." In contrast, pulmonary fibrosis and imaging-based diagnosis demonstrated limited recent activity, as "thin-section CT" and "high-resolution CT" maintained only a secondary role, reflecting a shift in focus toward immune-mediated mechanisms and therapeutic innovation.

conclusionAlthough the total number of chILD publications remains small, increasing attention to the field highlights the need for further contributions. Along with advances in understanding molecular pathogenesis, the recent surge of immunomodulatory therapies reflects a promising shift toward precision medicine through the identification and targeting of cellular mechanisms.

Indexed as

BibliometricsLung Diseases, InterstitialChildHumansPediatricsPulmonary Medicinebibliometric analysisinterstitial lung diseasespediatricVOSviewer

Identifiers

PMID41416617
PMCPMC12715830

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.