Evidence map›Paper›PMID 41416418›Full record

ArticleThe journal of adhesive dentistry2025

Urethane Tetramethacrylate Monomers and Nano-Fillers Enhance Dentin Bond Strength of a One-Step Universal Adhesive.

Yusuke Matsuki, Yumika Ida, Tomoki Iuchi, Wakana Oki, Kazuhide Yonekura, Yuta Utsumi, Masaomi Ikeda, Lorenzo Breschi, Keiichi Hosaka

Abstract read
In one paragraph

Article in The journal of adhesive dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yusuke Matsuki
Yumika Ida
Tomoki Iuchi
Wakana Oki
Kazuhide Yonekura
Yuta Utsumi
Masaomi Ikeda
Lorenzo Breschi
Keiichi Hosaka

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the effects of incorporating urethane tetramethacrylate (UTMA) monomers and inorganic nano-fillers on the bonding performance and mechanical properties of a next-generation one-step universal adhesive, Clearfil Universal Bond Quick 2 (UBQ2), with a focus on clarifying its improvements over the previous formulation. MATERIALS AND

methodsFive adhesive systems were investigated: UBQ2, two experimental variants lacking either UTMA (UBQ2-U) or nano-fillers (UBQ2-F), the predecessor adhesive (Clearfil Universal Bond Quick, UBQ), and a gold-standard two-step self-etch adhesive (Clearfil SE Bond 2, SE2). Microtensile bond strength (μTBS), bond layer thickness (L), ultimate tensile strength (UTS), and water sorption (Wsp) were evaluated.

resultsUBQ2 demonstrated significantly higher UTS and lower Wsp than UBQ2-U (P 0.001 and P = 0.03, respectively), indicating enhanced mechanical resilience and hydrolytic stability due to the presence of UTMA. Compared to UBQ, UBQ2 showed improved mechanical properties while maintaining comparable μTBS. The absence of nano-fillers (UBQ2-F) significantly reduced μTBS (P 0.05), confirming their critical role in bonding performance. Despite forming a thinner adhesive layer, UBQ2 achieved dentin bond strength comparable to SE2.

conclusionBy combining UTMA and nano-fillers, UBQ2 has improved wettability compared to conventional products, while also providing high bonding performance and mechanical properties with a one-step application. These findings support the development of universal adhesives through simplified clinical protocols and improved material properties. CLINICAL RELEVANCE: This study demonstrates that incorporating nano-fillers and UTMA into a one-step universal adhesive (UBQ2) enhances mechanical strength, reduces water sorption, and maintains high dentin bond strength. Clinically, UBQ2 offers a simplified yet reliable bonding performance comparable to SE2.

Indexed as

Dental BondingDentin-Bonding AgentsMethacrylatesPolyurethanesResin CementsUrethaneDental Stress AnalysisHumansMaterials TestingSurface PropertiesTensile StrengthWaterClearfil SE BondDentin-Bonding AgentsMethacrylatesPolyurethanesResin CementsUrethaneWaterdentin bonding performancemulti-functional monomernano-filleruniversal adhesive

Identifiers

PMID41416418
PMCPMC12720021

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.