Evidence map›Paper›PMID 41416406›Full record

ArticleMycoses2025

Incidence Rates of Candida Bloodstream Infections in Patients With Malignancies in a Comprehensive Cancer Centre.

Mohammad El-Atoum, George L Chen, John P Bonnewell, Brahm H Segal, Nikolaos G Almyroudis

Abstract read
In one paragraph

Article in Mycoses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad El-AtoumDepartment of Internal Medicine, University at Buffalo-The State University of New York, Buffalo, New York, USA.
George L ChenStem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
John P BonnewellDivision of Infectious Diseases, Department of Internal Medicine, Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York, USA.
Brahm H SegalDepartment of Internal and Hospital Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
Nikolaos G AlmyroudisDivision of Infectious Diseases, Department of Internal Medicine, Roswell Park Comprehensive Cancer Center and Jacobs School of Medicine and Biomedical Sciences, State University of New York, Buffalo, New York, USA.ORCID https://orcid.org/0000-0002-4230-3275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent literature indicates a decline in rates of candidemia in the general population.

objectivesTo analyse temporal trends in candidemia among patients with solid tumours and haematological malignancies admitted to a dedicated cancer centre.

methodsWe retrospectively reviewed all episodes of candidemia from July 2008 to June 2020 (12-year period). The incidence of candidemia was estimated as the number of new cases per 1000 patient days of hospital admission quarterly. A linear regression model was used to analyse changes in incidence rates.

resultsOver a 12-year period a total of 212 episodes of candidemia were identified with 90 (42.5%) occurring in patients with haematological malignancies and 122 (57.5%) in patients with solid tumours. The overall incidence of candidemia was 0.49 episodes per 1000 patient-days of admission per quarter. There was a significant decline in the incidence of candidemia overtime for the overall cohort (from 0.81 to 0.21 patient days per quarter, p < 0.001). This decline was statistically significant in patients with solid tumours (from 0.91 to 0.18 patient days per quarter, p < 0.001) with only a downward trend noted in patients with haematological malignancies (from 0.65 to 0.25 patient days per quarter, p = 0.052).

conclusionsWe observed a global decline in episodes of candidemia in patients with malignancies mainly driven by a decrease in patients with solid tumours. Patients with haematological malignancies continue to experience considerable rates of candidemia.

Indexed as

CandidemiaNeoplasmsAdultAgedAged, 80 and overCancer Care FacilitiesCandidaFemaleHematologic NeoplasmsHumansIncidenceMaleMiddle AgedRetrospective StudiesYoung Adultcandidemiahaematological malignanciesincidencesolid tumours

Identifiers

PMID41416406
PMCPMC12715748

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.