Evidence map›Paper›PMID 41416346›Full record

ArticleDEN open2026

Efficacy of the Stent-in-Stent Technique as a Rescue Method for Removing Embedded Metallic Biliary Stents.

Yasuhiro Komori, Susumu Hijioka, Yoshikuni Nagashio, Shota Harai, Daiki Yamashige, Kazunori Onuma, Keita Fujisaki, Daiki Agarie, Kohei Okamoto, Shin Yagi and 8 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yasuhiro KomoriDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Susumu HijiokaDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Yoshikuni NagashioDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Shota HaraiDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Daiki YamashigeDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Kazunori OnumaDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Keita FujisakiDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Daiki AgarieDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Kohei OkamotoDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Shin YagiDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Soma FukudaDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Masaru KuwadaDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Joshua Josef TorresDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.
Keijiro UedaDepartment of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Nao FujimoriDepartment of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Yutaka SaitoEndoscopy Division National Cancer Center Hospital Tokyo Japan.ORCID https://orcid.org/0000-0002-9574-7451
Yoshihiro OgawaDepartment of Medicine and Bioregulatory Science Graduate School of Medical Sciences Kyushu University Fukuoka Japan.
Takuji OkusakaDepartment of Hepatobiliary and Pancreatic Oncology National Cancer Center Hospital Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Self-expandable metal stents (SEMS) may become embedded because of tissue hyperplasia or tumor ingrowth, making their removal challenging. The stent-in-stent (SIS) method, which involves placing another SEMS inside to compress the tissue and aid removal, is a known rescue approach for stent removal. However, its efficacy across anatomical routes, optimal timing of removal, and predictors of difficult stent removal remain unclear. Methods: We retrospectively reviewed 17 patients treated between April 2018 and May 2025. Embedded stents were placed via the transpapillary route, endoscopic ultrasonography-guided hepaticogastrostomy (EUS-HGS), or choledochojejunal anastomosis. Technical success rates and adverse events were evaluated. Results: The overall technical success rate was 76.5%, with rates of 80.0%, 100%, and 33.3% for the transpapillary route, EUS-HGS, and choledochojejunal anastomosis, respectively. Three of the four failures occurred when removal was attempted within 4 weeks of the second stent placement. Stent removal was successful in 100% of the hyperplasia cases but in 60% of the ingrowth cases. Cholecystitis occurred in one case after the second stent placement. Conclusions: The SIS method is feasible for the transpapillary route and EUS-HGS but may show limited efficacy in choledochojejunal anastomosis. Stent removal 4 weeks after the second stent placement improves the success rate. The SIS method may be less effective in cases of malignant ingrowth.

Indexed as

biliary tract neoplasmsendoscopic retrograde cholangiopancreatographyhepaticojejunostomy anastomotic stricturepancreatic neoplasmself‐expanding metallic stent

Identifiers

PMID41416346
PMCPMC12710792

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.