Evidence map›Paper›PMID 41416345›Full record

ArticleEuropean clinical respiratory journal2026

Relation of changes in PEF and FEV

Leon L Csonka, Antti Tikkakoski, Anna P Tikkakoski, Jussi Karjalainen, Lauri Lehtimäki

Abstract read
In one paragraph

Article in European clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leon L CsonkaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Antti TikkakoskiDepartment of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland.
Anna P TikkakoskiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jussi KarjalainenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lauri LehtimäkiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAsthma diagnosis can be confirmed through the observation of significant bronchodilator response (BDR) measured by peak expiratory flow (PEF) during home monitoring or by forced expiratory volume in one second (FEV

aimTo use salbutamol administration after an exercise challenge test in children as a model of bronchodilation to assess how well relative change in PEF reflects improvement in lung function, as defined by increase in FEV

methodsWe retrospectively studied 326 free running exercise challenge tests with spirometry in children 6-16 years old. To assess congruency and differences between relative changes in PEF and FEV

resultsRelative change in PEF was, on average, greater than that in FEV

conclusionIncrease in PEF is not an accurate measure of BDR compared with increase in FEV

Indexed as

Asthmabronchodilationdiagnosticshome monitoringPEFspirometry

Identifiers

PMID41416345
PMCPMC12710255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.