ArticleCureus2025
Spontaneous Intracranial Hypotension: A Commonly Missed Cause of Secondary Headache.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spontaneous intracranial hypotension (SIH) is an uncommon but important cause of secondary headache that can closely mimic primary headache disorders, often leading to diagnostic delays. We present the case of a 50-year-old woman with a persistent, treatment-resistant orthostatic headache initially misdiagnosed as migraine, sinusitis, and perimenopausal symptoms. Brain MRI revealed a spontaneous subdural hematoma (SDH) along with classical features of SIH, while spinal MRI demonstrated a small longitudinal epidural fluid collection. Conservative management failed to relieve her symptoms; however, sequential non-targeted epidural blood patches (EBP) resulted in significant clinical and radiological improvement, with complete recovery noted at follow-up. This case underscores the importance of considering SIH in patients presenting with atypical or positional headaches, particularly when accompanied by SDH. Early recognition and appropriate intervention are crucial to prevent complications and optimise patient outcomes.
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