ArticleCureus2025
Early Weight-Bearing Following Ankle Fixation in a United Kingdom Major Trauma Centre: Real-World Adoption Versus a Contemporary Randomised Trial and British Orthopaedic Association Standards for Trauma.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Ankle fractures are common and place a substantial burden on services. Contemporary guidance generally permits weight-bearing as tolerated after stable fixation with early outpatient review. Recent randomised evidence suggests that beginning weight-bearing at around two weeks after open reduction and internal fixation (ORIF) can achieve at least comparable functional outcomes without increased complications and may be resource-efficient. Despite this, the adoption of early weight-bearing remains variable. We evaluated our centre's timing to first weight-bearing and early safety in the year following the dissemination of new evidence. Methods We conducted a single-centre retrospective cohort study at a UK major trauma centre (September 2024-August 2025). Adults (≥18 years) undergoing ankle ORIF were included; exclusions were hindfoot nails, tibial plafond (pilon) fractures, open fractures, or missing follow-up. Data sources were the local trauma database, operative notes, discharge summaries, fracture-clinic letters, imaging, and general practitioner records. Variables included age, sex, length of inpatient stay (LOS), fracture pattern (unimalleolar/bimalleolar/trimalleolar), posterior malleolus fixation (yes/no), syndesmosis fixation (none/screw/suture-button), and discharge device (cast/boot). The primary outcome was time to first weight-bearing (bands: at 2 weeks, 2-6 weeks, >6 weeks; sub-bands 6-8 and >8 weeks). Safety within eight weeks comprised unplanned emergency department/clinic contact, re-operation, and radiographic loss of reduction. Analyses used descriptive statistics (mean/standard deviation (SD); median/interquartile range (IQR)); between-group comparisons employed Kruskal-Wallis or Mann-Whitney U for days to weight-bearing and chi-square for proportions >6 weeks (two-sided p<0.05). Continuous outcomes (LOS, days to first weight-bearing) were non-normally distributed (Shapiro-Wilk p<0.001); hence, non-parametric tests were used. Results Forty-two patients were included. The mean age was 51.1 years (SD 16.5), with a median age of 49.5 years (IQR 39.2-62.5). LOS had a mean of 7.0 days (SD 7.9) and a median of 3.5 days (IQR 1.0-13.0). Time to first weight-bearing: at 2 weeks 2/42 (4.8%), 2-6 weeks 9/42 (21.4%), >6 weeks 31/42 (73.8%) (including 6-8 weeks 21/42 (50.0%), >8 weeks 10/42 (23.8%)). Safety ≤8 weeks in the 6-week or longer group showed unplanned contact 1/42 (2.4%), re-operation 0/42, loss of reduction 0/42, and delayed union 2/42 (4.8%). Safety margins in the 2-week group did not show any complications (0/42 in all parameters). Days to first weight-bearing did not differ significantly by fracture pattern (p=0.066) or syndesmosis fixation (p=0.383); posterior malleolus fixation was associated with longer time (Mann-Whitney p=0.036). Proportions exceeding six weeks did not differ significantly across subgroups. Conclusions Early weight-bearing after ankle ORIF was seldom implemented locally, with most patients first weight-bearing at ≥6 weeks despite reassuring short-term safety. In light of the recent clinical guidance, a default "weight-bearing as tolerated from two weeks" pathway (with clearly defined exceptions), standardised discharge/clinic instructions, and planned re-audit may improve implementation without compromising safety.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.