Evidence map›Paper›PMID 41416234›Full record

ArticleThe Journal of clinical and aesthetic dermatology2025

Hidradenitis Suppurativa Patients Experience a Significant Musculoskeletal Symptom Burden: A Quality Improvement Initiative Using the IDEOM MSK-Q.

Sarah Romanelli, Gretchen D Ball, Hassan Hamade, Mark Taliercio, Zachary Levy, Lourdes Perez-Chada, Joseph F Merola, Alice B Gottlieb

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In one paragraph

Article in The Journal of clinical and aesthetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sarah RomanelliMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.
Gretchen D BallMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.
Hassan HamadeMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.
Mark TaliercioMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.
Zachary LevyMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.
Lourdes Perez-ChadaDr. Perez-Chada is with the Department of Dermatology at Brigham and Women's Hospital at Harvard Medical School in Boston, Massachusetts.
Joseph F MerolaDr. Merola is with the Department of Dermatology and the Department of Medicine, Division of Rheumatology at the University of Texas Southwestern Medical Center in Dallas, Texas.
Alice B GottliebMs. Romanelli, Ms. Ball, Dr. Hamade, Dr. Taliercio, Mr. Levy, and Dr. Gottlieb are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with systemic inflammation and reports of increased prevalence and risk of inflammatory arthritis. Despite this, there is a lack of tools to assess musculoskeletal (MSK) symptoms in patients with HS. This quality improvement initiative aims to evaluate MSK symptom severity and impact in patients with HS using the International Dermatology Outcome Measures (IDEOM) Musculoskeletal Questionnaire (MSK-Q).

methodsOver 20 months, the IDEOM MSK-Q was distributed to 115 patients with HS receiving care at a single dermatology clinic. Demographic and clinical data were collected at all visits. The IDEOM MSK-Q is a 9-item tool scored on a 10-point scale, with subscores evaluating MSK symptom severity, impact on quality of life, and fatigue in the past week.

resultsAt baseline, 79.14 percent of patients reported joint symptoms, with 33.91 percent rating joint pain ≥7/10. Fatigue was also prevalent (47.82% rating ≥7/10). Higher HS severity was significantly correlated with greater MSK symptom burden, with the greatest impact reported in work and/or school activities and daily physical activities. Follow-up assessments suggested symptom improvement with systemic treatment, though statistical significance was not achieved. LIMITATIONS: This study has a small sample size and limited follow-up duration.

conclusionOur analysis shows substantial MSK symptom burden and fatigue among patients with HS. The IDEOM MSK-Q may be a valuable tool for assessing MSK symptoms and impact, supporting further development and validation in the HS population.

Indexed as

Hidradenitis suppurativainflammatory arthritismusculoskeletal symptomspatient-reported outcome measuresquality improvementspondyloarthritis

Identifiers

PMID41416234
PMCPMC12710871

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