ArticleJournal of asthma and allergy2025
Gut Microbiota Dysbiosis and Gut-Nasal Axis Alterations in Preschool Children with Allergic Rhinitis and Functional Constipation.
Article in Journal of asthma and allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Gut microbiome modulation in allergic rhinitis: from current evidence to emerging therapies.Frontiers in allergy · 2026Review
- Key messengers in the gut-nose axis: mechanisms of gut microbial metabolites in the immunomodulation of allergic rhinitis.Frontiers in immunology · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The comorbidity of allergic rhinitis (AR) and functional constipation (FC) in preschool children represents an emerging clinical entity; yet its underlying microbial mechanisms remain inadequately elucidated. This study sought to comprehensively characterize the gut microbiota (GM) profile and functional alterations in children with concurrent AR and FC (ARFC), with specific emphasis on the gut-nasal axis. Methods: In this cross-sectional analysis, fecal samples from 32 ARFC, 22 AR, and 21 healthy control (HC) children underwent Results: The ARFC group exhibited significant GM dysbiosis, including elevated α-diversity (Shannon index: 5.2 ± 0.3 vs HC 4.5 ± 0.4; Conclusion: ARFC comorbidity is characterized by a distinct GM signature featuring pathogenic expansion, metabolic dysfunction, and compensatory
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