Evidence map›Paper›PMID 41416158›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025

[Effects of Multiple Lifestyle Factors on Cardiovascular Biological Aging and Their Relative Contributions].

Jiajie Cai, Ning Zhang, Yi Xiang, Hongmei Zhang, Xiong Xiao

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Jiajie Cai/ （ 610041） Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0007-2455-2642
Ning Zhang/ （ 610041） Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Yi Xiang/ （ 610041） Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Hongmei Zhang/ （ 610041） Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Xiong Xiao/ （ 610041） Department of Epidemiology and Biostatistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0003-4471-7946

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the association between healthy lifestyle factors and cardiovascular biological aging, as well as the relative contributions of different lifestyle factors. Methods: Based on the clinical biochemical data and anthropometric data from the baseline survey of the UK Biobank (UKB), the Klemera-Doubal method (KDM) was used to establish cardiovascular biological age (CBA), and CBA acceleration was calculated accordingly. Multiple linear regression models were used to estimate the associations between healthy lifestyle factors and CBA acceleration. Then, the Quantile g-computation (QGC) was applied to evaluate the relative contributions of different lifestyle factors to CBA acceleration, with further analyses conducted separately for male and female populations. Additionally, stratified analyses were performed based on age, sex, body mass index (BMI), racial background, and family history of cardiovascular diseases to examine population heterogeneity. Results: A total of 251478 participants were included in the study. Both the overall healthy lifestyle score and each of the 7 lifestyle factors were negatively associated with CBA acceleration (overall lifestyle score: Conclusion: Lifestyle factors, as modifiable behaviors, can slow the rate of cardiovascular biological aging. Among these factors, alcohol consumption and diet may represent effective targets for intervention.

Indexed as

AgingCardiovascular DiseasesLife StyleAdultAgedAlcohol DrinkingBody Mass IndexDietFemaleHumansMaleMiddle AgedBiological ageCardiovascular biological ageCardiovascular biological agingHealthy lifestyle

Identifiers

PMID41416158
PMCPMC12709100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.