ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025
[Central Nervous System Infection After Neuroendoscopic and Microscopic Combined Hematoma Removal: Risk Factors and Construction of a Nomogram Prediction Model].
Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To analyze the risk factors associated with central nervous system (CNS) infection in patients after neuroendoscopic hematoma removal combined with and microscopic hematoma removal, and to construct and validate a nomogram prediction model. Methods: A total of 460 patients who underwent neuroendoscopic hematoma removal combined with microscopic hematoma removal at our hospital between January 2021 and December 2024 were retrospectively enrolled. The patients were assigned to a modeling cohort ( Results: The overall incidence of CNS infection in the 460 patients was 20.65% (95/460). According to the logistic regression analysis, the independent risk factors for CNS infection in patients after neuroendoscopic and microscopic combined hematoma removal included a history of diabetes mellitus (odds ratio [OR] = 3.431, 95% CI: 1.300-9.057), the Glasgow Coma Scale (GCS) score (OR = 0.574, 95% CI: 0.462-0.711), cerebrospinal fluid leakage (OR = 4.492, 95% CI: 1.430-14.116), operation duration (OR = 1.011, 95% CI: 1.004-1.019), duration of drainage tube placement (OR = 5.452, 95% CI: 2.423-12.268) and albumin (ALB) level (OR = 0.778, 95% CI: 0.720-0.840) ( Conclusion: The nomogram model based on history of diabetes mellitus, GCS score, cerebrospinal fluid leakage, operation duration, duration of drainage tube placement, and ALB level demonstrates high predictive performance for CNS infection after neuroendoscopy-assisted microscopic hematoma removal.
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