ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025
[Association Between Social Anxiety Symptoms and Brain Metabolism].
Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: In this study, we investigated the correlation between the scores for different Liebowitz Social Anxiety Scale (LSAS) subscale models and the metabolic activity in specific regions of the brain using Methods: A total of 39 cognitively normal participants (29 men and 10 women, aged 30-63 years) were enrolled. All participants underwent LSAS assessment and brain Results: LSAS subscale scores were significantly correlated with metabolic activity in specific brain regions. In the Safren model, the score for the observation by others subscale was positively correlated with the left fusiform gyrus ( Conclusion: Social anxiety symptoms are closely associated with metabolic changes in specific brain regions, including the left insula, left caudate tail, and right precuneus. Moreover, different social situations activate distinct brain regions. Compared with individuals with social anxiety disorder, normal individuals exhibit involvement of fewer brain regions when experiencing social anxiety. These findings provide new experimental evidence for understanding the neural mechanisms underlying social anxiety.
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