Evidence map›Paper›PMID 41416090›Full record

ReviewFrontiers in medicine2025

Transcutaneous auricular vagus nerve stimulation as an innovative approach for managing perioperative gastrointestinal dysfunction: a narrative review.

Ling Zhang, Qin Zhang, Xuefeng Yin, Ya Cao, Ye Chen, Zhonghua Li, Yu Shen, Keyu Fan, Mingxia Liu, Lu Qian and 5 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ling Zhang *Key Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Qin Zhang *Key Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Xuefeng Yin *Key Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Ya Cao *Key Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Ye ChenKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Zhonghua LiKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Yu ShenKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Keyu FanKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Mingxia LiuKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Lu QianKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Yunfeng WangKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Chongchun DaiKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Yanjuan RenKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Jingqiu WeiKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
He LiuKey Laboratory of Anesthesia and Analgesia Application Technology, Department of Anesthesiology and Clinical Research Center for Anesthesia and Perioperative Medicine, Huzhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative gastrointestinal dysfunction (POGD) is a prevalent and clinically significant complication following surgical procedures. It adversely impacts patient comfort, prolongs postoperative hospitalization duration, and increases the risk of perioperative complications and unplanned readmissions, thereby contributing to higher healthcare costs. Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising neuromodulatory intervention. As a non-invasive technique, it offers several advantages, including ease of administration, a favorable safety profile, and high patient acceptability. This narrative review outlines the pathophysiological mechanisms underlying POGD, the anatomical basis of the vagus nerve, the technical parameters of taVNS, and its therapeutic mechanisms in managing postoperative gastrointestinal disturbances. The objective is to support the development of a comprehensive treatment approach for patients with POGD, promoting accelerated recovery.

Indexed as

pathophysiological mechanismspostoperative gastrointestinal dysfunctionpostoperative ileustranscutaneous auricular vagus nerve stimulationvagus nerve

Identifiers

PMID41416090
PMCPMC12708935

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.