Evidence map›Paper›PMID 41416010›Full record

ArticleFrontiers in integrative neuroscience2025

Multiplexed detection of nuclear immediate early gene expression reveals hippocampal neuronal subpopulations that engage in the acquisition and updating of spatial experience.

Thu-Huong Hoang, Denise Manahan-Vaughan

Abstract read
In one paragraph

Article in Frontiers in integrative neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thu-Huong HoangDepartment of Neurophysiology, Medical Faculty, Ruhr University Bochum, Bochum, Germany.
Denise Manahan-VaughanDepartment of Neurophysiology, Medical Faculty, Ruhr University Bochum, Bochum, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired spatial representations are not static. Each re-exposure to the spatial environment stimulates retrieval of the stored experience followed by information re-encoding, including updating if the environment has changed. It remains unclear if the same neurons are involved in these three events. Here, we used a multiplexed fluorescence

Indexed as

fluorescence in situ hybridizationhippocampusimmediate early genesrodentsspatial updating

Identifiers

PMID41416010
PMCPMC12708613

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.