Evidence map›Paper›PMID 41415937›Full record

ArticleLaryngoscope investigative otolaryngology2025

Heart Rate as a Predictor of 6-Month Pneumonia Risk in Patients With Dysphagia.

Yuval Nachalon, Nogah Nativ-Zeltzer, Yosef Kula, Anne Tran, Stephanie Reshma Warrior, Peter C Belafsky

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuval NachalonDepartment of Otolaryngology, Head and Neck Surgery and Maxillofacial Surgery Tel-Aviv Sourasky Medical Center Tel-Aviv Israel.ORCID https://orcid.org/0000-0001-6202-4647
Nogah Nativ-ZeltzerGray Faculty of Medical and Health Sciences Tel Aviv University Tel Aviv Israel.
Yosef KulaHealth Psychology Unit, Institute of Psychology University of Graz Austria.
Anne TranSchool of Medicine University of California Davis California USA.
Stephanie Reshma WarriorSchool of Medicine University of California Davis California USA.
Peter C BelafskyCenter for Voice and Swallowing, Department of Otolaryngology, Head & Neck Surgery University of California Davis California USA.ORCID https://orcid.org/0000-0003-0288-2839

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine whether resting heart rate (HR) or heart rate variability (HRV) derived from finger photoplethysmography (PPG) predicts 6-month pneumonia risk in patients with dysphagia. HRV reflects autonomic regulation of inflammation which may predispose to respiratory complications. Methods: A total of 301 patients who underwent a videofluoroscopic swallow study (VFSS) in 2020-2021 were enrolled. Prior to VFSS, resting HR was measured using the CorSense HRV finger sensor (ELITE HRV). Additional HRV metrics, including the standard deviation of normal-to-normal intervals (SDNN) and the root mean square of successive differences (RMSSD) were collected from a subset of 153 participants. Pneumonia incidence was assessed at 3 and 6 months through phone interviews and medical record review. Results: The mean age was 66.3 ± 12.5 years, and 38% were female. Twenty patients (7%) developed pneumonia, with 75% of cases occurring within 3 months. Patients who developed pneumonia had higher resting HR than those who did not (83.4 vs. 74.3 bpm, Conclusion: Elevated resting HR, though within the normal range, was associated with increased pneumonia risk in patients with dysphagia. This may reflect underlying inflammation or autonomic dysfunction. Because comorbidities, medications, and VFSS severity were not accounted for, these findings should be interpreted as preliminary. Resting HR may represent a simple, non-invasive tool for pneumonia risk stratification in this population, but larger studies are needed for validation. Level of Evidence: 2.

Indexed as

dysphagiaheart rate variabilitypneumoniapneumonia riskpredictive biomarkers

Identifiers

PMID41415937
PMCPMC12710430

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.