ArticleSultan Qaboos University medical journal2025
Genetic Screening of Genome-Wide Association Studies-Derived Risk Loci for Type 2 Diabetes Mellitus:
Article in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Re: Genetic Screening of Genome-Wide Association Studies-Derived Risk Loci for Type 2 Diabetes Mellitus:Sultan Qaboos University medical journal · 2026Article
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4 authors.
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Abstract
Objectives: This case-control study investigated the association of three novel South Asian genome-wide association studies (GWAS)-derived type 2 diabetes mellitus (T2DM) susceptibility gene polymorphisms in the North Indian population. Methods: The study was conducted at King George's Medical University, Lucknow, India, between January 2022 and December 2023. Three single nucleotide polymorphisms (SNPs) were genotyped: rs2028299 (C>A) near the AP3S2 gene, rs1802295 (C>T) near the VPS26A gene, and rs16861329 (C>T) near the ST6GAL1 gene. Genotyping was performed using polymerase chain reaction (PCR) followed by Sanger sequencing of PCR amplicons. The relationship between T2DM and various anthropometric traits was examined in a cohort of 100 North Indian participants, comprising 60 individuals with T2DM and 40 ethnically matched healthy controls. Enrolment was based on inclusion and exclusion criteria, with participants required to provide written informed consent. Diagnostic criteria included glycated haemoglobin (HbA1c) ≥ 6.5% and fasting plasma glucose ≥126 mg/dL. Results: Significant differences in genotype and allele frequencies were observed for AP3S2-rs2028299 ( Conclusion: The AP3S2-rs2028299 CA variant and ST6GAL1-rs16861329 CT variant may serve as potential genetic biomarkers for T2DM development in the North Indian population.
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