Evidence map›Paper›PMID 41415866›Full record

Trial reportSultan Qaboos University medical journal2025

Effectiveness of Silk Fibroin Dressing Compared to Saline Dressing on Wound Healing in Post-Laparotomy Patients with Superficial Surgical Site Infections:

Bhanu P Chandavaram, Uday S Kumbhar, Reddy A P

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Clinical progress and prospects of biodegradable intestinal stents.American journal of translational research · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bhanu P ChandavaramDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.ORCID 0009-0009-3605-416X
Uday S KumbharDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.ORCID 0000-0003-3365-082X
Reddy A PDepartment of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.ORCID 0000-0001-6175-5480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to determine and compare the effectiveness of silk fibroin dressing and normal saline dressing in terms of wound healing time, as assessed by Dr Kamal's Adaptive Wound Healing Score (KAWHS). Methods: A single-blinded, randomised controlled trial was conducted at a tertiary hospital from November 2022 to November 2023. A total of 142 patients with superficial surgical site infections (SSIs) post-laparotomy were randomised into two groups: silk fibroin dressing (n = 71) and saline dressing (n = 71). The primary outcome, wound healing, was assessed using KAWHS on days 5, 10, and 15. Secondary outcomes included exudate amount (measured by gauze weight), length of hospital stay, and scar characteristics assessed at three months using the Vancouver Scar Scale (VSS). Results: The silk fibroin group demonstrated significantly faster wound healing, with a mean duration of 13.92 ± 2.38 days (95% confidence interval [CI]: 13.36-14.48) compared to 17.41 ± 2.73 days (95% CI: 16.76-18.06) in the saline dressing group ( Conclusions: Silk fibroin dressing was more effective than saline dressing in accelerating wound healing and reducing exudate in patients with superficial SSIs following laparotomy. Short-term benefits were evident, whereas long-term outcomes such as scar formation appeared comparable.

Indexed as

BandagesFibroinsLaparotomySaline SolutionSurgical Wound InfectionWound HealingAdultAgedFemaleHumansLength of StayMaleMiddle AgedSingle-Blind MethodTreatment OutcomeFibroinsSaline SolutionCicatrixLaparotomyOcclusive DressingsSilk FibroinsSurgical Site InfectionsWound Healing

Identifiers

PMID41415866
PMCPMC12709218

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.