Evidence map›Paper›PMID 41415835›Full record

ArticleFrontiers in nutrition2025

Serum metabolomics and gut microbiota analysis reveal the lipid-lowering effects of fermented triple-bean soup in high-fat diet-fed mice.

Zina Hao, Xinyi Li, Zongze Li, Menghan Ma, Yue Xi, Li Yu, Yimeng Wang, Baogang Zhang, Yunhe Xu, Lili Zhang

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zina HaoCollege of Food and Health, Jinzhou Medical University, Jinzhou, China.
Xinyi LiCollege of Food and Health, Jinzhou Medical University, Jinzhou, China.
Zongze LiCollege of Basic Medicine, Jinzhou Medical University, Jinzhou, China.
Menghan MaCollege of Food and Health, Jinzhou Medical University, Jinzhou, China.
Yue XiThe Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Li YuCollege of Basic Medicine, Jinzhou Medical University, Jinzhou, China.
Yimeng WangThe Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Baogang ZhangDiscipline Inspection and Supervision Office, Jinzhou Medical University, Jinzhou, China.
Yunhe XuCollege of Animal Husbandry and Veterinary Medicine, Jinzhou Medical University, Jinzhou, China.
Lili ZhangCollege of Food and Health, Jinzhou Medical University, Jinzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-bean soup (TBS), a traditional Chinese functional food, was innovatively fermented with lactic acid bacteria (FTBS) to enhance its hypolipidemic potential. Using a multi-omics approach integrating 16S rRNA sequencing and serum metabolomics, we systematically investigated FTBS's effects on high-fat diet (HFD)-induced metabolic disorders in mice. FTBS significantly alleviated HFD-induced metabolic disorders, outperforming UFTBS. It remodels the microbial ecosystem by suppressing obesogenic bacteria, restoring microbial diversity and F/B balance, and increasing the abundance of

Indexed as

fermented triple-bean soupfunctional foodgut microbiotalipid-loweringmetabolomics

Identifiers

PMID41415835
PMCPMC12708937

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.