ReviewBiodesign research2025
Recent advances on protein engineering for improved stability.
Review in Biodesign research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Engineering a Novel Cofactor-Versatile Short-Chain Dehydrogenase for Efficient Synthesis of Chiral Alcohols.Biotechnology and bioengineering · 2026Article
- Reengineering a thermostable keratinase past the boiling point.Applied and environmental microbiology · 2026Article
- Thermostability Engineering in Therapeutic Antioxidant Enzymes: From Molecular Fundamentals to Oxidative Stress Applications.International journal of molecular sciences · 2026Review
- An Archaeal Cyclodextrin Glycosyltransferase fromInternational journal of molecular sciences · 2026Article
- Advances in polyethylene biodegradation and bioconversion: Microbial, enzymatic, and biotechnological insights.Engineering microbiology · 2026Review
- Superchaotropic Stabilization of Monomeric Protein States.Biomacromolecules · 2026Article
- JanusDDG: a physics-informed neural network for sequence-based protein stability via two-fronts attention.Communications biology · 2026Article
- Ancestral Sequence Reconstruction for Novel Bifunctional Glutathione Synthetase with Enhanced Thermostability and Catalytic Efficiency.Foods (Basel, Switzerland) · 2026Article
- Decoding Protein Stabilization: Impact on Aggregation, Solubility, and Unfolding Mechanisms.Journal of chemical information and modeling · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stability is a crucial factor influencing applicability of industrial biocatalysts, and enzymatic operations in partial organic solvents and higher temperatures are preferable since organic solvents may improve the solubility of the substrates, and the reaction rates are often higher at elevated temperatures. This review aims to summarize recent advances for engineering enzymes to meet the industrial needs for solvent and thermostability and offer insights in the advances in methodologies utilizing B-factors, ancestral reconstructions, or machine learning approaches.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.