Evidence map›Paper›PMID 41415704›Full record

Observational studyRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2025

Effect of vaginal pH on the efficacy of the dinoprostone vaginal insert for cervical ripening in patients with an unfavorable bishop score.

Sílvia Serrano, Inês Martins, Marina Gato, Carina Simões, Andreia Fonseca, Helena Ferreira, Mónica Centeno

Abstract readObservational Study
In one paragraph

Observational study in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sílvia SerranoCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-0544-2698
Inês MartinsCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0009-0005-9213-5651
Marina GatoCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0009-0002-9741-8333
Carina SimõesCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0009-0007-8129-5101
Andreia FonsecaCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-4074-638X
Helena FerreiraCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0009-0004-1243-7207
Mónica CentenoCentro Hospitalar Universitário Lisboa Norte Hospital de Santa Maria Lisbon Portugal Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal.ORCID https://orcid.org/0000-0001-9749-5932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to evaluate the effect of vaginal pH on the efficacy of the dinoprostone vaginal insert for cervical ripening in patients with unfavorable Bishop Score. Methods: Prospective observational cohort study, conducted at a Portuguese tertiary hospital. Term pregnant women with a singleton pregnancy and vertex presentation who had indication for labor induction with Bishop's Score ≤ 6 were included. Vaginal pH was measured with high accuracy strips before vaginal examination for Bishop Score was performed. The intravaginal dinoprostone insert (Propess Results: A total of 75 women were included, with a gestational age of 39 ± 1,2 weeks. Mean initial vaginal pH was 4.67 ± 0.51. Mean variation of Bishop Score was 1.8 ± 2.3 points. There was a weak correlation between vaginal pH and changes on the Bishop Score with dinoprostone vaginal insert use (ρ = -0.123; p = 0.3). Conclusion: Vaginal pH does not appear to be a major influencer of the efficacy of dinoprostone vaginal insert for cervical ripening.

Indexed as

Cervical RipeningDinoprostoneLabor, InducedOxytocicsVaginaAdministration, IntravaginalAdultCohort StudiesFemaleHumansHydrogen-Ion ConcentrationPregnancyProspective StudiesYoung AdultDinoprostoneOxytocicsBishop's ScoreCervical ripeningDinoprostoneVaginal pH

Identifiers

PMID41415704
PMCPMC12711240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.