Evidence map›Paper›PMID 41415623›Full record

ArticleEngineering biology

Creating Enforceable Biosecurity Standards for Nucleic Acid Providers.

Jacob Beal, Tessa Alexanian

Abstract read
In one paragraph

Article in Engineering biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Implementing emerging customer screening standards for nucleic acid synthesis.Frontiers in bioengineering and biotechnology · 2026
    Article
  4. The evolution of the United States nucleic acid screening policies.Frontiers in bioengineering and biotechnology · 2026
    Review
  5. Article
  6. Article
  7. Developing a standard definition for sequences of concern.Frontiers in bioengineering and biotechnology · 2026
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jacob BealRTX BBN Technologies Cambridge Massachusetts USA.ORCID https://orcid.org/0000-0002-1663-5102
Tessa AlexanianInternational Biosecurity and Biosafety Initiative for Science (IBBIS) Geneva Switzerland.ORCID https://orcid.org/0000-0003-1108-7124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although there is broad agreement among biosecurity experts that nucleic acid synthesis providers should screen orders for potential threats, there is no agreed upon mechanism to verify whether a provider is implementing effective screening practices. This leads to economic costs for responsible actors, unverifiable claims of screening, and regulatory hesitation. The sequence biosecurity risk consortium (SBRC) aims to address these problems by developing a standard definition of 'sequences of concern' based on a scientific assessment of biosecurity risk from synthetic nucleic acids. Building on this effort, we outline a roadmap for moving from aspirational to enforceable standards via industry-led standards development, with support and participation from government regulators.

Indexed as

bio‐economybiosecuritystandardisation

Identifiers

PMID41415623
PMCPMC12710665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.