Evidence map›Paper›PMID 41415580›Full record

ReviewFrontiers in pharmacology2025

Gonzalo Fuentes-Barros, Sebastián Castro-Saavedra, Nicolás Montalva, Marco Mellado, Antonia Diaz-Valdés, Claudia Guerrero-Rodríguez, Javier Echeverría

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gonzalo Fuentes-BarrosSAPHYCHEM, Santiago, Chile.
Sebastián Castro-SaavedraSAPHYCHEM, Santiago, Chile.
Nicolás MontalvaCentro de Investigación en Sociedad y Salud, Facultad de Ciencias Sociales y Artes, Universidad Mayor, Santiago, Chile.
Marco MelladoCentro de Investigación en Ingeniería de Materiales, Universidad Central de Chile, Santiago, Chile.
Antonia Diaz-ValdésCentro de Investigación en Sociedad y Salud, Facultad de Ciencias Sociales y Artes, Universidad Mayor, Santiago, Chile.
Claudia Guerrero-RodríguezSAPHYCHEM, Santiago, Chile.
Javier EcheverríaDepartamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Purpose: The aim is to present the first comprehensive review of the current state of knowledge regarding traditional uses, ethnopharmacology, chemical composition, pharmacokinetic profile, and biological activities of Methodology: Literature data on the traditional uses, ethnopharmacology, chemistry, and bioactivity of Results and discussion: Traditional uses include its role as a food source for prehistoric populations and ethnomedicinal applications for liver diseases, rheumatism, and infections. The aerial parts are rich in polyphenols, including chlorogenic acid, epicatechin, procyanidins, quercitrin, rutin, and hyperoside, as well as essential oils derived from the leaves. While it contains various alkaloids, only reticuline is present in significant amounts, contributing to the species' highly variable chemical composition. Studies evaluating the biological and pharmacological properties of its extracts and constituents are limited to a few Conclusion: The review highlights the entire existing ethnographic and cultural context of

Indexed as

alkaloidsCryptocarya albacryptocarya genusessential oilspeumopharmacologyphenolic compoundsphytochemistry

Identifiers

PMID41415580
PMCPMC12709134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.