ArticleFrontiers in surgery2025
Case Report: Application of combined transplantation of multiple autologous flaps in preventing empty pelvis syndrome after radical surgery for isolated sacrococcygeal recurrence of anal canal squamous.
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anal canal carcinoma is a rare malignancy, accounting for less than 3% of gastrointestinal tumors. Recurrent anal canal carcinoma, which occurs in less than 1% of cases, is often accompanied by severe complications. Surgery plays a crucial role in improving patients' quality of life and controlling systemic paraneoplastic syndromes. This article reports a case of a 52-year-old female patient with recurrent anal canal squamous cell carcinoma (pT4bN0M0, Stage IIIB) 7 months after comprehensive treatment, complicated by rectovaginal fistula (RVF) and hypercalcemia of malignancy (HCM). Following multidisciplinary team (MDT) discussions, an innovative approach combining free omental packing with gracilis myocutaneous flap was adopted for the treatment of an isolated sacrococcygeal recurrent tumor after anal canal squamous cell carcinoma surgery. A tumor mass with a maximum diameter of 12.5 cm was completely resected. Postoperative pathological examination confirmed that no cancer cells were detected in multiple biopsies of the free resection margin, achieving R0 resection. After surgery, the patient's serum calcium level and serum squamous cell carcinoma antigen (SCC) returned to normal. Meanwhile, the bilateral combined myocutaneous flaps survived completely, RVF symptoms disappeared, the patient's quality of life was significantly improved, and the survival prognosis was enhanced.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.