Evidence map›Paper›PMID 41415521›Full record

ArticleClinical case reports2025

Thoraco-Omphalopagus Conjoined Twins Following IVF With Day 5 Embryo Transfer: A Rare Case Report and Multidisciplinary Management Approach.

Patryk Piekos, Natalia Ravelo, Rodrigo Ruano, George Attia

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patryk PiekosReproductive Endocrinology and Infertility Division, Department of Obstetrics, Gynecology and Reproductive Sciences University of Miami, Miller School of Medicine Miami Florida USA.ORCID https://orcid.org/0000-0002-5534-4172
Natalia RaveloMaternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences University of Miami, Miller School of Medicine Miami Florida USA.
Rodrigo RuanoMaternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences University of Miami, Miller School of Medicine Miami Florida USA.
George AttiaReproductive Endocrinology and Infertility Division, Department of Obstetrics, Gynecology and Reproductive Sciences University of Miami, Miller School of Medicine Miami Florida USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjoined twinning is a rare and severe complication of monozygotic pregnancies. Assisted reproductive technologies (ART), including in vitro fertilization (IVF), may increase the risk of such anomalies. We report a case of thoraco-omphalopagus conjoined twins following a day 5 embryo transfer after IVF with intracytoplasmic sperm injection (ICSI). The diagnosis was made by ultrasound at 8 weeks' gestation and confirmed the presence of fused thoracic and abdominal structures with a shared heart. The pregnancy was managed through multidisciplinary counseling, and termination was performed following spontaneous fetal demise. This case underscores the importance of early imaging, detailed embryologic understanding, and coordinated care in managing rare IVF-associated anomalies.

Indexed as

assisted reproductive technology (ART)conjoined twinsday 5 embryo transferintracytoplasmic sperm injection (ICSI)in vitro fertilization (IVF)thoraco‐omphalopagus

Identifiers

PMID41415521
PMCPMC12710522

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.