Evidence map›Paper›PMID 41415516›Full record

ArticleClinical case reports2025

Aseptic Sinusitis: A New Phenotype of Immune-Related Rhinosinusitis in the Era of Immune Checkpoint Inhibitors.

Josephine Yalovitser, Kenny Nguyen, Kelly McKenna, Shahid Ahmed, Carolyn Orgain

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josephine YalovitserLarner College of Medicine at the University of Vermont Burlington Vermont USA.ORCID https://orcid.org/0009-0003-1701-6439
Kenny NguyenLarner College of Medicine at the University of Vermont Burlington Vermont USA.
Kelly McKennaDepartment of Surgery, Division of Otolaryngology University of Vermont Medical Center Burlington Vermont USA.
Shahid AhmedDepartment of Medicine, Division of Hematology and Oncology University of Vermont Medical Center Burlington Vermont USA.
Carolyn OrgainDepartment of Surgery, Division of Otolaryngology University of Vermont Medical Center Burlington Vermont USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present two novel cases of aseptic sinusitis resulting from PDL-1 checkpoint inhibitor use. Prompt identification and diagnosis and a multidisciplinary approach with oncology and rheumatology are imperative. High-dose steroids are preferable to antibiotics or antihistamines due to primary cancer treatment outcomes.

Indexed as

ear nose and throatimmunologyoncologyotolaryngologypharmacology and pharmacy

Identifiers

PMID41415516
PMCPMC12710534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.