Evidence map›Paper›PMID 41415450›Full record

ArticlebioRxiv : the preprint server for biology2025

Graph embeddings for identifying symmetries in Connectomes.

Haozhe Shan, Ashok Litwin-Kumar

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Haozhe ShanKavli Institute for Brain Science, Department of Neuroscience, Columbia University.ORCID 0000-0002-1168-4861
Ashok Litwin-KumarKavli Institute for Brain Science, Department of Neuroscience, Columbia University.ORCID 0000-0003-2422-6576

Funding

Relating structure and function in synapse-level wiring diagramsRF1DA060772 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LITWIN-KUMAR, ASHOK · 2024 to 2024
$1.1M
NIDA NIH HHS RF1 DA060772
6 · The paper itself

Abstract

In many circuit models of neural computation, synaptic connections between neurons are organized according to their tuning to the variables being processed. The connectivities of canonical neural network models of head direction, spatial navigation, and orientation selectivity obey this principle and contain symmetries related to the angular and spatial variables they operate on. We develop a graph embedding algorithm to identify such symmetries. The algorithm segregates structure related to cell type from that related to the symmetries we seek to identify, distinguishing it from standard embedding methods. Our method successfully identifies rotational and translational symmetries in heading direction and visual projection neuron circuits using a connectome of the adult

Identifiers

PMID41415450
PMCPMC12709479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.