Evidence map›Paper›PMID 41415407›Full record

ArticlebioRxiv : the preprint server for biology2025

The cyclic nucleotide binding sites of Swiss-Cheese, the

Alexander Law, Jill Wentzell, Alexandre Bettencourt da Cruz, Luke Marney, Doris Kretzschmar

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander LawOregon Institute of Occupational Health Sciences, Oregon Health & Sciences University, Portland, OR, USA.
Jill WentzellOregon Institute of Occupational Health Sciences, Oregon Health & Sciences University, Portland, OR, USA.
Alexandre Bettencourt da CruzOregon Institute of Occupational Health Sciences, Oregon Health & Sciences University, Portland, OR, USA.
Luke MarneyDepartment of Chemistry, Oregon State University, Corvallis, OR, USA.
Doris KretzschmarOregon Institute of Occupational Health Sciences, Oregon Health & Sciences University, Portland, OR, USA.

Funding

SWS/NTE function in neurodegeneration and axonopathyR01NS047663 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETZSCHMAR, DORIS · 2004 to 2013
$2.7M
Trapped Ion Mobility Spectrometry Quadrupole Time-of-Flight SystemS10OD032323 · OD · OREGON STATE UNIVERSITY · PI MAIER, CLAUDIA S · 2023 to 2023
$1.3M
NIH HHS S10 OD032323NINDS NIH HHS R01 NS047663
6 · The paper itself

Abstract

Mutations in Swiss-cheese (SWS) or its vertebrate ortholog PNLPA6, also called Neuropathy Target Esterase (NTE), cause progressive neuronal degeneration in

Indexed as

Boucher-NeuhäuserGordon HolmesNeuropathy target esterasePNPLA6

Identifiers

PMID41415407
PMCPMC12710771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.