Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Soojin YuDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0002-0730-0239
Seong-Ryong YuDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0003-0025-3860
Myung Kyung ChoiDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0002-1841-0644
Jae-Hyung JinDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0002-0589-9444
Vikas YadavDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0003-2650-9035
Hee Seong ChoiDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0009-0002-3457-2800
Eui-Seong KimKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54531, Republic of Korea.ORCID 0009-0007-7836-4583
Hyun-Woo KimKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54531, Republic of Korea.ORCID 0000-0002-2780-4047
Jae-Seok JeongKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54531, Republic of Korea.ORCID 0000-0002-4635-8302
Do-Kyun KimKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54531, Republic of Korea.ORCID 0000-0002-3457-4868
Joseph HeitmanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0001-6369-5995
Hyun-Soo ChoDepartment of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0003-4067-4715
Kyung-Tae LeeKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54531, Republic of Korea.ORCID 0000-0002-0068-6220
Yong-Sun BahnDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0001-9573-5752
Funding
Calcineurin signaling cascades governing Cryptococcus virulenceR01AI172451 · NIAID · DUKE UNIVERSITY · PI JOSEPH HEITMAN · 2023 to 2026
$2.7M
NIAID NIH HHS R01 AI172451
6 · The paper itself
Abstract
Adenylyl cyclase (AC) is the central regulator of cAMP signalling in fungal pathogens, yet fungal ACs uniquely contain a protein phosphatase 2C (PP2C) domain whose function remains unclear. Here, we characterise the PP2C domain of the AC Cac1 in the human pathogen
Indexed as
Adenylyl cyclaseCyclic AMPFungal meningitisPP2CProtein kinase A
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in · full record | OpenQuestion