Evidence map›Paper›PMID 41415367›Full record

ArticlebioRxiv : the preprint server for biology2025

The N-terminal region of malaria vaccine candidate

Rolando Garza, Jeffrey M Marchioni, Jared D Honeycutt, Nicholas K Hurlburt, Caroline Torres, Anakaren Garcia, Eva Loranc, Emily Yemington, Dalton Towers, Isaac Ssewanyana and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Rolando GarzaDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.
Jeffrey M MarchioniDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.
Jared D HoneycuttDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Nicholas K HurlburtVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0001-9891-916X
Caroline TorresDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.
Anakaren GarciaDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.
Eva LorancDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.
Emily YemingtonDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.
Dalton TowersDepartment of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA.
Isaac SsewanyanaInfectious Disease Research Collaboration, Kampala, Uganda.
Marie PanceraVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.ORCID 0000-0001-9217-6270
Jason J LavinderDepartment of Chemical Engineering, University of Texas at Austin, Austin, TX, USA.
Prasanna JagannathanDepartment of Medicine, Division of Infectious Diseases, Stanford University, Stanford, California, USA.ORCID 0000-0001-6305-758X
Bryan GreenhouseDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Sebastiaan BolDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.
Evelien M BunnikDepartment of Microbiology, Immunology & Molecular Genetics, University of Texas at San Antonio Health Science Center, San Antonio TX, USA.ORCID 0000-0003-4003-3053

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Computational models of naturally acquired immunity to falciparum malariaU01AI150741 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUTTE, ATUL J, GREENHOUSE, BRYAN R · 2020 to 2024
$7.4M
Defining conserved epitopes on polymorphic malaria antigensR01AI153425 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BUNNIK, EVELIEN MARGARETHA · 2021 to 2025
$2.7M
South Texas Medical Scientist Training Program (STX-MSTP)T32GM145432 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Jose E Cavazos, Ratna K Vadlamudi · 2023 to 2026
$2.3M
FACSAria Fusion cell sorter for Flow Cytometry Shared ResourceS10OD030432 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BERTON, MICHAEL T · 2022 to 2022
$596k
Analyzing the function and antibody-mediated inhibition of the malaria vaccine candidate PF3D7_1136200F30AI176697 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GARZA, ROLANDO · 2024 to 2025
$81k
NCI NIH HHS P30 CA054174NIAID NIH HHS F30 AI176697NIAID NIH HHS R01 AI153425NIAID NIH HHS U01 AI150741NIAID NIH HHS U19 AI089674NIGMS NIH HHS T32 GM145432NIH HHS S10 OD030432Wellcome Trust
6 · The paper itself

Abstract

The development of malaria blood-stage vaccines has been hampered by sequence variation in many

Indexed as

autoantibodiesB cellsinhibitioninvasionmalariamonoclonal antibodiespolyreactivity

Identifiers

PMID41415367
PMCPMC12709472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.