Evidence map›Paper›PMID 41415309›Full record

ArticleFrontiers in physiology2025

Hemoglobin mass does not increase in able-bodied individuals after consecutive days of acute intermittent hypoxia.

Andrew S Harding, Katelyn D Noyes, Aviva K Pollet, Sewan Kim, Andrew Q Tan

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Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew S HardingNeuroRecovery Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Katelyn D NoyesApplied Exercise Science Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Aviva K PolletNeuroRecovery Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Sewan KimNeuroRecovery Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Andrew Q TanNeuroRecovery Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged exposure to hypoxia can elevate serum erythropoietin (EPO) and may eventually increase hemoglobin mass. However, whether intermittent hypoxia consisting of breathing short intervals alternated with normoxia (acute intermittent hypoxia; AIH) can trigger erythropoiesis and lead to increases in hemoglobin mass is less clear. Therefore, the purpose of this study was to investigate the effect of consecutive days of AIH on hemoglobin mass. Participants (n = 18) were exposed to 4 consecutive days of AIH consisting of fifteen 90 s intervals of breathing ∼9% O

Indexed as

altitudecardiorespiratory fitnessErythropoietinhemoglobin massoxygen saturation

Identifiers

PMID41415309
PMCPMC12708231

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.