SynthesisFrontiers in public health2025
Impact of caregiver interventions on caregiver burden in adult traumatic brain injury: a systematic review and meta-analysis.
Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Healthcare Professionals' Perceptions of the Palliative Care Needs of Patients with Severe Brain Injury and Their Caregivers: A Qualitative Study.Brain sciences · 2026Article
- Caregiver Burden and Support for People with Neurological Disorders: Findings from a Polish Cross-Sectional Study.Journal of clinical medicine · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Traumatic brain injury (TBI) has been known to cause physical and psychological dysfunction among patients. Most family members face numerous physical and psychological difficulties in caregiving, yet effective interventions remain limited. This study aims to (a) identify the effects of caregiver interventions on caregiver burden for traumatic brain injury patients, (b) evaluate the effects of these programs on caregivers' psychological distress. Methods: A systematic search was conducted in Pubmed, Medline and PsycINFO to search for randomized control trials (RCTs) that report the effects of caregiver interventions on care partners of TBI patients above the age of 18. The primary outcome was caregiver burden, which was measured mainly using the Zarit Burden Interview (ZBI). The secondary outcome was psychological distress, with the Brief Symptom Inventory-18 (BSI-18) as the main assessment used. The RoB-2 tool was used to assess the risk of bias. Results: Thirteen RCTs were identified after screening. Meta-analysis of the primary outcome (ZBI) showed significant improvements ( Conclusion: Results suggest that caregiver interventions are effective in improving caregiver burden and psychological distress in the future. However, due to high risk of bias in studies, the conclusion should be interpreted with caution before clinical application. Higher quality research should be conducted to ensure the effectiveness of caregiver programs.
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Registered trials
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