Evidence map›Paper›PMID 41415193›Full record

ArticleRSC advances2025

Quinoline and coumarin isoxazole derivatives: synthesis, antitumor evaluation and molecular docking studies with Bcl-2.

Martina Piškor, Marina Ter, Leentje Persoons, Dirk Daelemans, Ahmed Adel, Mutasem O Taha, Astrid Milić, Mirela Sedić, Silvana Raić-Malić

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martina PiškorDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb Marulićev trg 19 10000 Zagreb Croatia sraic@fkit.unizg.hr.ORCID https://orcid.org/0000-0002-0433-066X
Marina TerDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb Marulićev trg 19 10000 Zagreb Croatia sraic@fkit.unizg.hr.
Leentje PersoonsKU Leuven, Department of Microbiology, Immunology and Transplantation, Molecular Genetics and Therapeutics in Virology and Oncology Research Group, Rega Institute 3000 Leuven Belgium.ORCID https://orcid.org/0000-0002-7898-0868
Dirk DaelemansKU Leuven, Department of Microbiology, Immunology and Transplantation, Molecular Genetics and Therapeutics in Virology and Oncology Research Group, Rega Institute 3000 Leuven Belgium.
Ahmed AdelFaculty of Pharmacy and Medical Sciences, University of Petra Amman 11196 Jordan.
Mutasem O TahaDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan Amman 11942 Jordan.ORCID https://orcid.org/0000-0002-4453-072X
Astrid MilićSelvita d.o.o. Zagreb 10000 Croatia.
Mirela SedićCentre for Applied Bioanthropology, Institute for Anthropological Research Zagreb Croatia.
Silvana Raić-MalićDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb Marulićev trg 19 10000 Zagreb Croatia sraic@fkit.unizg.hr.ORCID https://orcid.org/0000-0001-5021-8970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to conventional therapies in pancreatic and hematologic malignancies highlights the need for novel agents that selectively induce tumor cell death. This study presents the design, synthesis, and evaluation of new quinoline- and coumarin-derived isoxazole analogs (7a-e, 8a-f, 9a-e) and their Re(i) and Ru(ii) complexes (7b

Identifiers

PMID41415193
PMCPMC12709234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.