Evidence map›Paper›PMID 41415133›Full record

ArticleJournal of mid-life health

Vitamin D and Vitamin K: Synergistic Roles and Emerging Evidence for Combined Supplementation.

Ankur Khandelwal, Kashif Akhtar Ahmed, Priyadarshi Dikshit

Abstract read
In one paragraph

Article in Journal of mid-life health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ankur KhandelwalDepartment of Anaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences, Guwahati, Assam, India.
Kashif Akhtar AhmedDepartment of Orthopaedics, All India Institute of Medical Sciences, Guwahati, Assam, India.
Priyadarshi DikshitDepartment of Neurosurgery, All India Institute of Medical Sciences, Guwahati, Assam, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synergistic role of Vitamin D (VD) and Vitamin K (VK) in maintaining skeletal and cardiovascular health has garnered increasing scientific interest. While VD is well known for its role in calcium metabolism, VK, particularly its K2 isoform, ensures that calcium is deposited in bones and not in soft tissues. Recent evidence suggests that the interplay between these two fat-soluble vitamins may have significant implications for bone health, vascular integrity, and chronic disease prevention. This editorial explores current research on their combined supplementation, potential therapeutic benefits, and the caution warranted in clinical practice.

Indexed as

Osteoporosissynergismvascular calcificationVitamin DVitamin K

Identifiers

PMID41415133
PMCPMC12711164

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.