ArticleAmerican journal of translational research2025
Propofol and remifentanil anesthesia improves cerebral oxygen balance and accelerates recovery in patients undergoing craniotomy for traumatic brain injury.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
objectiveTo evaluate the effect of propofol combined with remifentanil anesthesia on the cerebral oxygen supply-demand balance during craniotomy in patients with traumatic brain injury (TBI).
methodsA total of 180 patients who underwent craniotomy for TBI from January 2020 to December 2024 were retrospectively included and divided into two groups according to the intraoperative anesthesia regimen: a control group (n=88, sevoflurane and remifentanil) and a study group (n=92, propofol and remifentanil).
resultsThe times to spontaneous respiration recovery, orientation recovery, eye opening upon verbal command, tracheal extubation, and exit from the operating room were significantly shorter in the study group than in the control group (
conclusionsPropofol combined with remifentanil anesthesia may accelerate the postoperative recovery in TBI patients undergoing craniotomy, reduce oxidative stress and cerebral reperfusion injury, and improve cerebral oxygen supply-demand balance, with fewer adverse reactions.
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