Evidence map›Paper›PMID 41415101›Full record

ArticleAmerican journal of translational research2025

The impact of different muscle relaxation depths on the placement of the i-gel laryngeal mask and the analysis of influencing factors on postoperative sore throat: a retrospective study based on general anesthesia in adult patients.

Shilei Cao, Zhigang Huang, Yu Xiao, Feifei Wu, Tangkun Wang, Chenghui Zhao, Liqun Hu

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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Shilei CaoDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Zhigang HuangDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Yu XiaoDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Feifei WuDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Tangkun WangDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Chenghui ZhaoDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.
Liqun HuDepartment of Anesthesiology, Tongling Municipal Hospital Tongling 244000, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the impact of varying neuromuscular blockade (NMB) depths on the success of i-gel laryngeal mask airway (LMA) insertion and to examine determinants of postoperative sore throat (POST) in adult patients under general anesthesia.

methodsThis retrospective case-control study included 140 adults who underwent general anesthesia with i-gel LMA from November 2023 to July 2024. Subjects were categorized into four groups based on neuromuscular blockade depth: deep (Group A), moderate (Group B), shallow (Group C), and minimal (Group D), as measured by Train-of-Four ratio. We assessed baseline characteristics, i-gel insertion success rates, complications, and POST severity at multiple intervals after surgery. Factors affecting POST were analyzed using correlation analysis and logistic regression models.

resultsModerate NMB (Group B) demonstrated significantly higher first-attempt i-gel insertion success (91.43%) compared to deep (62.86%), shallow (60.00%), and minimal (60.00%) NMB groups (P < 0.01). No significant differences in complication rates were observed among groups. POST severity at 0.5 hours was significantly lower in Group B but equalized across all groups at 6 and 24 hours. Multivariate analysis identified smoking history (OR = 0.258, 95% CI: 0.116-0.574, P < 0.001) and blood sputum presence (OR = 0.337, 95% CI: 0.099-1.148, P = 0.082) as inversely associated with POST, while higher ASA classification (OR = 0.421, 95% CI: 0.185-0.956, P = 0.039) and longer placement time (OR = 0.174, 95% CI: 0.060-0.500, P = 0.001) were significant predictors.

conclusionThis study demonstrates that moderate muscle relaxation significantly enhances i-gel LMA insertion success and reduces early POST severity. The identification of protective factors against POST highlights the importance of developing personalized perioperative strategies to improve patient comfort and airway management outcomes.

Indexed as

airway managementgeneral anesthesiai-gel laryngeal mask airwayinsertion successneuromuscular blockadepostoperative sore throat

Identifiers

PMID41415101
PMCPMC12709328

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