ArticleAmerican journal of translational research2025
Exploring the effect of the waist-rubbing method on immune balance in rats with lumbar disc herniation.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate the therapeutic effect of the waist-rubbing method on lumbar disc herniation (LDH) and explore its immunoregulatory mechanisms.
methodsForty Sprague-Dawley rats were randomly divided into three groups: control, model, and treatment groups. The control group did not undergo modeling, while LDH models were established in the other two groups. Behavioral tests were conducted on all rats at designated time points, and neurological function scores were compared among groups. After 15 days of corresponding interventions, peripheral blood samples were collected for flow cytometric analysis of T-cell subsets. Serum levels of corticosterone (CORT), glucocorticoid receptor α (GR
resultsCompared with the control group, the model group showed significantly increased Th1/Th2 and Th17/Treg ratios, elevated serum levels of IFN-γ and IL-17, and decreased CORT, GR
conclusionThe waist-rubbing method may alleviate autoimmune disorders in LDH by enhancing hypothalamic-pituitary-adrenal (HPA) axis activity and restoring Th1/Th2 and Th17/Treg balance, providing mechanistic support for the traditional concept of "tonifying the kidney to relieve pain".
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