Evidence map›Paper›PMID 41414925›Full record

ArticleEuropean heart journal2026

Childhood-onset RASopathy-associated hypertrophic cardiomyopathy, diastolic dysfunction, and arrhythmias.

Olga Dimitra Boleti, Sotirios Roussos, Emanuele Monda, Gabrielle Norrish, Ella Field, Elena Cervi, Athanasios Bakalakos, Precylia Fernandes, Karen McLeod, Maria Ilina and 15 more

Abstract read
In one paragraph

Article in European heart journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Olga Dimitra BoletiInstitute of Cardiovascular Sciences, University College London, 62 Huntley St, London WC1E 6DD, UK.ORCID 0000-0002-0254-0217
Sotirios RoussosDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Emanuele MondaInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', Monaldi Hospital, Naples, Italy.
Gabrielle NorrishInstitute of Cardiovascular Sciences, University College London, 62 Huntley St, London WC1E 6DD, UK.ORCID 0000-0003-2064-237X
Ella FieldCentre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.
Elena CerviCentre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK.ORCID 0000-0003-2612-1014
Athanasios BakalakosInstitute of Cardiovascular Sciences, University College London, 62 Huntley St, London WC1E 6DD, UK.
Precylia FernandesDepartment of Paediatric Cardiology, Royal Hospital for Children, Glasgow, UK.
Karen McLeodDepartment of Paediatric Cardiology, Royal Hospital for Children, Glasgow, UK.
Maria IlinaDepartment of Paediatric Cardiology, Royal Hospital for Children, Glasgow, UK.
Bernadette KhodaghalianDepartment of Paediatric Cardiology, Alder Hey Hospital, Liverpool, UK.
Caroline JonesDepartment of Paediatric Cardiology, Alder Hey Hospital, Liverpool, UK.
Fuensanta EscuderoPediatric Cardiology Department, Virgen de la Arrixaca Hospital, Murcia, Spain.
Fransisco CastroPediatric Cardiology Department, Virgen de la Arrixaca Hospital, Murcia, Spain.
Mohamed Najih Liaqath AliDepartment of Paediatric Cardiology, Southampton General Hospital, Southampton, UK.
Tara BharuchaDepartment of Paediatric Cardiology, Southampton General Hospital, Southampton, UK.ORCID 0000-0003-2713-8125
Gauri NepaliThe Heart Unit, Birmingham Children's Hospital, Birmingham, UK.
Vinay BholeThe Heart Unit, Birmingham Children's Hospital, Birmingham, UK.
Grazia Delle DonneDepartment of Paediatric Cardiology, Leeds General Infirmary, Leeds, UK.
Elspeth BrownDepartment of Paediatric Cardiology, Leeds General Infirmary, Leeds, UK.
Juan Ramon GimenoPediatric Cardiology Department, Virgen de la Arrixaca Hospital, Murcia, Spain.
Perry Mark ElliottInstitute of Cardiovascular Sciences, University College London, 62 Huntley St, London WC1E 6DD, UK.
Cordula WolfEuropean Reference Network for Rare, Low Prevalence, or Complex Disease of the Heart (ERN GUARD Heart).ORCID 0000-0003-4701-5843
Giuseppe LimongelliInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', Monaldi Hospital, Naples, Italy.
Juan Pablo KaskiInstitute of Cardiovascular Sciences, University College London, 62 Huntley St, London WC1E 6DD, UK.ORCID 0000-0002-0014-9927

Funding

Clinical Academic Research Partnership MR/T024062/1Max's FoundationMedical Research CouncilOnassis Foundation
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease progressionHypertrophic cardiomyopathyLongitudinalNoonanPaediatricRASopathies

Identifiers

PMID41414925
PMCPMC13183176

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.