SynthesisAnnals of medicine2025
Global prevalences of erythropoiesis-associated micronutrient deficiencies (iron, folate, and vitamin B
Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Folate Deficiency Alters microRNA Expression and Transcriptomic Networks in a Human Trophoblast Model.Nutrients · 2026Article
- Determinants of Folate and Vitamin BNutrients · 2026Article
- Diagnosis and treatment of vitamin B12 deficiency in children.Frontiers in nutrition · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDeficiencies of iron, folate, and vitamin B12 micronutrients are considered a global public health issue. These deficiencies not only lead to anemia but are also linked to numerous short- and long-term health risks for both mothers and children. This study aimed to estimate the global prevalence of erythropoiesis-associated micronutrient deficiencies (iron, folate, and vitamin B12) in pregnant women. MATERIALS AND
methodsWe systematically searched three databases, including PubMed, Embase, and Scopus, along with a manual search for observational studies published up to August 26, 2024. Data extraction was independently screened by two reviewers. Random-effects models were employed to pool data on prevalences of iron, folate, and vitamin B12 deficiencies among pregnant women. We identified 43 studies from 28 countries.
resultsGlobal pooled prevalences of single iron, folate, and vitamin B12 deficiencies were 28.4% (95% CI, 21.1-37%), 11.1% (95% CI, 3.9-27.5%), and 17.1% (95% CI, 8.8-30.6%), respectively. Pooled prevalences of double micronutrient deficiencies of iron or folate were 53.1% (95% CI, 49.8-56.5%) and 49.6% (95% CI, 46.2-53%), respectively; double micronutrient deficiencies of folate or vitamin B12 were 6.2% (95% CI, 1.2-25.8%) and 11.8% (95% CI, 3.3-34.1%), respectively. Pooled prevalences of triple micronutrient deficiencies of iron or folate or vitamin B12 were 36.1% (95% CI, 13.1-68%), 34.3% (95% CI, 16.9-57.3%), and 12.6% (95% CI, 7-74.8%), respectively.
conclusionThe findings highlight the high prevalences of erythropoiesis-related micronutrient deficiencies in pregnant women worldwide. Targeted interventions to mitigate these deficiencies during pregnancy.
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