Trial reportJournal of cosmetic dermatology2025
Novel Application of Oral Postbiotics for Skin Condition in Healthy Middle-Aged Women: A Randomized, Double-Blind, and Placebo-Controlled Study.
Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Novel Application of Oral Postbiotics for Skin Condition in Healthy Middle-Aged Women: A Randomized, Double-Blind, and Placebo-Controlled Study.Journal of cosmetic dermatology · 2025Trial
- Microbiome-Directed Bioactive Strategies in Skin Aging: Mechanistic Insights and Precision Nanocarrier Delivery Approaches.Molecules (Basel, Switzerland) · 2026Review
- Postbiotics as Emerging Strategy Targeting Obesity- and Aging-Related Breast Cancer-Prospects in Prophylaxis and Therapy.Life (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
background and purposeLatilactobacillus sakei KABP-065 derived from pickled vegetables of East Asia can improve skin condition in patients with atopic dermatitis through a mechanism that suppresses immune hyperactivity. Here we investigated whether KABP-065 postbiotics can improve the facial skin condition of healthy middle-aged women.
methodsJapanese women (n = 60) aged ≥ 30 to < 50 years who met inclusion criteria were randomly assigned to postbiotic or placebo groups. The participants consumed capsules containing either heat-treated KABP-065 (1 × 10
resultsCheek skin moisture and transepidermal water loss improved for both groups after the intervention. The postbiotic group had significantly improved skin elasticity relative to the placebo group. A stratified analysis of participants in their 40s showed that, compared to the placebo group, the postbiotic group had a greater improvement in skin elasticity and a significantly greater improvement in cheek moisture. No exacerbation of gastrointestinal symptoms was seen with postbiotic supplementation, and the frequency of adverse events was similar between the postbiotic and placebo groups.
conclusionKABP-065 postbiotics could be effective for improving the skin condition of healthy women aged ≥ 30 to < 50 years, especially those in their 40s.
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Registered trials
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