SynthesisCardiovascular ultrasound2025
The predictive value of right ventricle speckle tracking echocardiography in patients undergoing cardiac surgery, a systematic review and meta-analysis.
Synthesis in Cardiovascular ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
backgroundRight ventricular (RV) dysfunction is a critical predictor of adverse outcomes in cardiac surgery patients. The assessment of right ventricular global longitudinal strain (GLS) echo has emerged as a promising tool for detecting early RV dysfunction. This meta-analysis evaluates the predictive value of RV GLS in these patients.
methodsA comprehensive literature search was conducted. The primary outcomes included pooled diagnostic performance measures, including sensitivity, specificity, and the diagnostic odds ratio (DOR). A multiple-cutoff model was employed to determine the optimal RV-GLS threshold.
resultsTen observational studies involving 583 patients were included. RV-GLS demonstrated strong diagnostic accuracy, with a pooled area under the summary receiver operating characteristic curve (AUC) of 0.90 (95% CI: 0.82-1.00). The pooled DOR was 6.34 (95% CI: 3.20-12.57) with no heterogeneity (I² = 0%). Sensitivity was 0.79 (95% CI: 0.69-0.86; I² = 57.2%) and specificity was 0.78 (95% CI: 0.71-0.84; I² = 20.8%). The risk of publication bias was low (LFK index = 0.6). A multiple-threshold model identified - 15.25% as the optimal RV-GLS cutoff, achieving balanced sensitivity and specificity of 0.7423.
conclusionsRV-GLS demonstrates excellent predictive value for RV dysfunction in cardiac surgery patients.
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