Evidence map›Paper›PMID 41413607›Full record

ArticleAnimal microbiome2025

Decoding the dynamics of calves' respiratory and gut microbiota: exploring stability, resistance, and individual patterns.

Núria Mach, Maverick Monié-Ibanes, Fatima Z Sikht, Marie-Claude Hygonenq, Gwendoline Pot, Hortensia Robert, David Bars, Yves Farizon, Eric Richard, Xavier Nouvel and 4 more

Abstract read
In one paragraph

Article in Animal microbiome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Núria MachIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France. nuria.mach@inrae.fr.
Maverick Monié-IbanesIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Fatima Z SikhtIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Marie-Claude HygonenqIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Gwendoline PotIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Hortensia RobertIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
David BarsUnit of Biomarkers and Susceptibility (UBS), Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), L'Hospitalet del Llobregat, Barcelona, 08908, Spain.
Yves FarizonGenPhySe, INRAE, ENVT, Universty of Toulouse, Castanet Tolosan, France.
Eric RichardLABÉO, Saint-Contest, France.
Xavier NouvelIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Christine CittiIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Eric BaranowskiIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Mariette DucatezIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.
Gilles MeyerIHAP, INRAE, ENVT, University of Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the early-life interplay between microbiota, host, and environment by longitudinally monitoring nasal and gut microbiota in 30 veal calves over their first five months of life. Microbial composition and stability were highly compartmentalized. Fecal communities showed increasing biomass, diversity, and homogeneity with age. Conversely, nasal microbiota remained less diverse and highly variable between individuals, likely influenced by mucociliary clearance and transient colonization. Environmental factors, diet, and clinical indicators were associated with both microbial communities, alongside distinct cytokine profiles. As calves matured, microbiota dynamics and composition covaried across body sites, reflecting systemic immune development and environmental adaptations. This study provides a comprehensive, multi-layered characterization of microbial dynamics, identifying the first month of life as a critical window for interventions targeting the fecal microbiota. The nasal microbiota, by contrast, remains flexible and amenable to modulation throughout the production cycle.

Identifiers

PMID41413607
PMCPMC12713259

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.