Evidence map›Paper›PMID 41413579›Full record

ArticleBMC veterinary research2025

The applicability of the Migratest

Roman Wójcik, Dawid Tobolski, Grzegorz Zwierzchowski

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roman WójcikDepartment of Microbiology and Clinical Immunology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, Olsztyn, 10-719, Poland.
Dawid TobolskiDepartment of Large Animal Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-787, Poland.
Grzegorz ZwierzchowskiDepartment of Biochemistry, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, Olsztyn, 10-719, Poland. grzegorz.zwierzchowski@uwm.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe chemotactic activity of peripheral blood granulocytes in lambs supplemented with a multi-strain probiotic formulation (containing three Lactobacillus strains: Lactobacillus plantarum AMT14, Lactobacillus plantarum AMT4, and Lactobacillus rhamnosus AMT15, and one Bifidobacterium animalis AMT30 strain) was evaluated with the use of the Migratest

resultsThe study found that lambs fed a probiotic supplement had significantly enhanced white blood cell migration to areas of infection. This was measured using the Migratest® kit, which assesses L-selectin expression. Lower L-selectin levels were linked to improved chemotactic activity. Probiotic supplementation resulted in decreased L-selectin expression in lambs compared to the control group, suggesting a potential mechanism for the observed immune benefits.

conclusionThe study found that dietary probiotics can boost the immune system of lambs by increasing the ability of their white blood cells to migrate to sites of infection. Using the Migratest® kit, researchers were able to accurately measure this improvement. This discovery suggests that tested a multi-strain probiotic formulation may have positive effects on the immune systems of other animals as well and warrants further investigation into the underlying mechanisms.

Indexed as

BifidobacteriumChemotaxisGranulocytesLactobacillusProbioticsAnimal FeedAnimalsDietDietary SupplementsMaleSheepChemotaxisGranulocytesLambsMigratest®Probiotic

Identifiers

PMID41413579
PMCPMC12849581

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.