Evidence map›Paper›PMID 41413557›Full record

ArticleJournal of orthopaedic surgery and research2025

Minimally invasive endoscopic treatment for unicameral bone cysts: technique and outcomes in a series of 33 pediatric and adolescent patients.

Lenian Zhou, Zengxin Jiang, Zeng Zhang, Qingcheng Yang, Ting Yuan

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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Lenian ZhouDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Zengxin JiangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Zeng ZhangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Qingcheng YangDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. tjyqc@163.com.
Ting YuanDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. terrenceyuan@gmail.com.

Funding

National Natural Science Foundation of China 82402855
6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy and safety of a minimally invasive endoscopic protocol-combining curettage, sclerotherapy, and injectable bone grafting-in the treatment of unicameral bone cysts (UBCs).

methodsFrom March 2019 to August 2024, 33 pediatric and adolescent patients with UBCs were treated using a standardized minimally invasive endoscopic curettage combined with sclerotherapy and injectable bone grafting at our institution. The cohort included 24 males and 9 females, with a mean age of 10.1 years (range 4-20 years). Patients were followed for an average of 48.4 months (range 12-76 months). Radiographic healing rates, functional score, and complications were assessed.

resultsAccording to the modified Neer classification, complete or partial radiographic healing was achieved in 30 cases (90.9%), while 3 cases experienced persistent or recurrent cyst (9.1%). Almost all patients recovered excellent function. No postoperative pathological fractures or growth plate disturbances were observed during a mean follow-up of 48.4 months. Complications were limited to one episode of transient pain and one case of mild swelling, both self-limiting without intervention. Postoperative hospitalization was brief (mean, 1.2 days), and cosmetic outcomes were excellent, with minimal portal scars, far less conspicuous than those from traditional open procedures.

conclusionEndoscopic minimally invasive surgery combining curettage, sclerotherapy, and injectable bone grafting appears to be a safe and effective option for the management of UBCs in children and adolescents, achieving high healing rates and low complication risks. Nevertheless, given the single-arm design and limited sample size, larger controlled studies with long-term follow-up are needed to confirm these findings.

Indexed as

Bone CystsBone TransplantationCurettageEndoscopyMinimally Invasive Surgical ProceduresSclerotherapyAdolescentChildChild, PreschoolCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleRetrospective StudiesTreatment OutcomeAdolescentBone tumorEndoscopicMinimally invasivePediatricUnicameral bone cysts

Identifiers

PMID41413557
PMCPMC12828951

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