Evidence map›Paper›PMID 41413393›Full record

ArticleJournal of the American Heart Association2026

Racial Differences in Recurrent Acute Myocardial Infarction: Findings From the ARIC Cohort.

Duygu Islek, Alvaro Alonso, Wayne Rosamond, Anna Kucharska-Newton, Yejin Mok, Kunihiro Matsushita, Silvia Koton, Michael Joseph Blaha, Viola Vaccarino

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A pipeline for enabling path-specific causal fairness in observational health data.Proceedings of the ... Conference on Fairness, Accountability, and Transparency · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Duygu IslekDepartment of Epidemiology, Rollins School of Public Health Emory University Atlanta GA USA.ORCID 0000-0001-6041-2320
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health Emory University Atlanta GA USA.ORCID 0000-0002-2225-8323
Wayne RosamondDepartment of Epidemiology University of North Carolina at Chapel Hill, Gillings School of Global Public Health Chapel Hill NC USA.ORCID 0000-0001-5271-074X
Anna Kucharska-NewtonDepartment of Epidemiology University of North Carolina at Chapel Hill, Gillings School of Global Public Health Chapel Hill NC USA.ORCID 0000-0001-9864-467X
Yejin MokDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-8511-604X
Kunihiro MatsushitaDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-7179-718X
Silvia KotonDepartment of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.ORCID 0000-0002-9327-7505
Michael Joseph BlahaDivision of Cardiology, School of Medicine Johns Hopkins University Baltimore MD USA.ORCID 0000-0001-5138-9683
Viola VaccarinoDepartment of Epidemiology, Rollins School of Public Health Emory University Atlanta GA USA.ORCID 0000-0002-9054-0654

Funding

THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - COORDINATING CENTER - TASK AREA B.2 AND B.375N92022D00001 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COUPER, DAVID · 2022 to 2025
$13.7M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00003 · NHLBI · UNIVERSITY OF MINNESOTA · PI LUTSEY, PAMELA L. · 2022 to 2025
$5.1M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WAGENKNECHT, LYNNE E · 2022 to 2025
$5.0M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00004 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI WINDHAM, BEVERLY GWEN · 2022 to 2025
$4.8M
THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY - FIELD CENTER - TASK ORDER 01, TASK AREA A75N92022D00002 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CORESH, JOSEF · 2022 to 2025
$4.7M
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
NHLBI NIH HHS 75N92022D00001NHLBI NIH HHS 75N92022D00002NHLBI NIH HHS 75N92022D00003NHLBI NIH HHS 75N92022D00004NHLBI NIH HHS 75N92022D00005NHLBI NIH HHS K24 HL148521
6 · The paper itself

Abstract

backgroundWe examined racial differences in recurrent nonfatal acute myocardial infarction (AMI) and fatal coronary heart disease (CHD) among ARIC (Atherosclerosis Risk in Communities) cohort participants who survived a first AMI (1987-2017) and assessed whether socioeconomic and cardiovascular risk factors contribute to observed differences.

methodsWe analyzed 422 Black and 1245 White ARIC participants who survived an incident AMI during follow-up. Incidence rates of recurrent AMI and fatal CHD were calculated by race. Proportional hazards models examined differences after adjustment for socioeconomic and cardiovascular risk factors, with race-sex interactions tested.

resultsThe mean±SD age at the time of the first incident AMI was 69.3±9.0 years for Black and 70.7±9.5 years for White participants. The incidence rate per 1000 person-years was higher in Black participants than White participants both for recurrent nonfatal AMI (incidence rate, 32.4 [95% CI, 26.8-38.8] versus 22.8 [95% CI, 20.2-25.6]) and for fatal CHD (34.2 [95% CI, 28.4-40.7] versus 17.9 [95% CI, 15.7-20.4]). In age- and sex-adjusted models, the hazard ratios comparing Black versus White participants were 1.70 (95% CI, 1.36-2.13) for recurrent nonfatal AMI and 2.10 (95% CI, 1.67-2.34) for fatal CHD. The racial differences were statistically not significant after adjustment for socioeconomic and cardiovascular risk factors. There were no significant race and sex interactions for outcomes.

conclusionsBlack participants have higher rates of recurrent nonfatal AMI and fatal CHD after an initial AMI compared with White participants. These disparities are mostly explained by socioeconomic and cardiovascular risk factors.

Indexed as

Black or African AmericanCoronary DiseaseHealth Status DisparitiesMyocardial InfarctionWhiteAgedFemaleHumansIncidenceMaleMiddle AgedProspective StudiesRace FactorsRecurrenceRisk AssessmentRisk Factorsfatal coronary artery diseaseracial disparitiesrecurrent myocardial infraction

Identifiers

PMID41413393
PMCPMC12909037

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.