Evidence map›Paper›PMID 41413340›Full record

ReviewAnalytical and bioanalytical chemistry2026

Research advances in capillary electrophoresis coating technology for protein analysis.

Mengyuan Xu, Wei Pan, Yichen Tian, Hailin Cong, Bing Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengyuan XuCollege of Chemistry and Chemical Engineering, College of Life Sciences, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China.
Wei PanCollege of Chemistry and Chemical Engineering, College of Life Sciences, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China.
Yichen TianCollege of Chemistry and Chemical Engineering, College of Life Sciences, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China.
Hailin CongCollege of Chemistry and Chemical Engineering, College of Life Sciences, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China.
Bing YuCollege of Chemistry and Chemical Engineering, College of Life Sciences, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China. yubing198@qdu.edu.cn.

Funding

Exploration project of the State Key Laboratory of BioFibers and EcoTextiles of Qingdao University TSKT202101Medical Plus Key Project of Qingdao University YX2024201National Key R&D Program of China 2024YFE0104100National Natural Science Foundation of China 22074072National Natural Science Foundation of China 22274083Science and Technology Planing Project of South District of Qingdao City 2022-4-005-YYShandong Provincial Natural Science Foundation ZR2022LZY022Shandong Provincial Natural Science Foundation ZR2023LZY005
6 · The paper itself

Abstract

Capillary electrophoresis (CE) is primarily a technique for separating and analyzing samples based on their differing physicochemical properties. CE is renowned for its rapid analytical capability and minimal sample requirements, rendering it widely applicable in the biomedical field. However, the silica hydroxyl groups (Si-OH) present on the capillary wall can adversely affect protein separation. Modifying capillary walls through physical adsorption or chemical bonding can suppress protein adsorption, thereby enhancing separation efficiency. This review examines the causes and solutions for protein adsorption, types of capillary coatings, and the application of coated capillaries in protein separation. Finally, it outlines future trends for coated capillaries in protein separation.

Indexed as

ProteinsAdsorptionAnimalsElectrophoresis, CapillaryHumansSilicon DioxideProteinsSilicon DioxideCapillary electrophoresisChemical bonding coatingPhysical adsorption coatingProtein separation

Identifiers

PMID41413340

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.